Thursday, October 31, 2019

Degrees of Homicide Assignment Example | Topics and Well Written Essays - 250 words

Degrees of Homicide - Assignment Example dad saw the kidnapper the next day in an interview and in sudden rage, the dad grabbed a revolver from a nearby officer and killed the kidnapper (â€Å"Manslaughter†). Another example is when Dan comes home to find his wife in bed with Victor. In the heat of the moment, Dan picks up a golf club from next to the bed and strikes Victor in the head, killing him instantly (â€Å"Manslaughter: Voluntary†). Involuntary manslaughter involves the death of a human being, but without the intent required for murder, comprising elements such as (1) the killing of another human being was unintentional; (2) the death occurred either during the commission of an unlawful act not amounting to a felony or as the result of criminal negligence; and (3) the defendant’s unlawful act or negligence caused the death (Wallace 8). For instance: two kids were street-racing, one lost control and hit a crowd of spectators. Two of the spectators were killed. The one who lost control was charged with involuntary manslaughter (â€Å"Manslaughter†). Another picture is when a driver is running a red light and then crashing into another car, which kills the other driver (â€Å"When†). Negligent manslaughter is a new type of homicide that the Model Penal Code developed in response to the fact that the voluntary and involuntary manslaughter are difficult to apply in certain situations. It is the unintentional killing of another human being caused by the negligence of the defendant including elements that (1) the killing of another human being was unintentional; (2) the death resulted from a negligent act by the defendant; and (3) the defendant’s negligence caused the death (Wallace 8). A case of negligent manslaughter is: D, an anaesthetist, failed to observe during an eye operation that the tube inserted in V’s mouth had become detached from the ventilator, causing V to suffer a cardiac arrest and eventually die (â€Å"Cases†). A different circumstance is when D pointed a gun at V, without

Tuesday, October 29, 2019

American Literature Essay Example for Free

American Literature Essay Characteristics The literature is as diverse as the cultures that created it, but there are often common elements such as stories explaining creation or natural forces. Major Writers or Works Oral narratives: Myths; legends; songs; creation stories from groups such as the Zuni, Aztec, Navajo, Lakota, Seneca, Tlingit, Cherokee, Blackfoot, Cree, Inuit, and many more. †¢Exploration Period, 1492-1607 Characteristics The first European writings about North America are written in this period. European writings describe the explorers travels and impressions of the continent and its Native  people. Major Writers or Works Prose: Christopher Columbus, Alvar Nunez Cabeza de Vaca, Bernal Diaz del Castillo, Thomas Harriot, and Samuel de Champlain. Oral narratives: Seneca legend How America was discovered. †¢Colonial Period, 1607-c. 1765 Characteristics The Colonial period was dominated by Puritan beliefs and thus literature of this period is usually historical, religious, or didactic. The most common genres were tracts, polemics, journals, narratives, sermons, and some poetry. The first slave narratives were written at this time. Imaginative literature was rare; in some colonies, it was banned for being immoral. Major Writers or Works Poetry: Michael Wigglesworth, Anne Bradstreet, Edward Taylor. Prose: John Smith, Roger Williams, Cotton Mather, Jonathan Edwards Sinners in the Hands of an Angry God, Benjamin Franklins Poor Richards Almanacks. Narratives: Mary Rowlandsons A Narrative of the Captivity and Restoration of Mrs. Mary Rowlandson. †¢Revolutionary Period, 1765-1790 Characteristics This period begins with the passing of the Stamp Act in England and ends in 1790. The Revolutionary period usually refers to writings that are politically motivated, either in support of British rule, in support of American patriotism and independence, or relating to the Constitution. Major Writers or Works Prose: Thomas Jeffersons Autobiography, Declaration by the Represent-atives of the United States of America, Thomas Paines Common Sense, Alexander Hamilton and James Madisons Federalist Papers. Drama: Royall Tylers The Contrast. Verse and Ballads: Yankee Doodle, The Liberty Song. †¢Early National Period, 1775-1828 Characteristics. During this period, a body of distinctly American imaginative literature began to emerge. As with the novel, poetry, essays, and sketches also began to flourish. The publishing world and readership in America also began to grow. Slave narratives were published with increasing frequency. This period is sometimes called the Federalist period after the conservative federalists in power at the time. Major Writers or Works Poetry: Phillip Freneau, William Cullen Bryant, Phillis Wheatley. Prose: Judith Sargent Murray, Mercy Otis Warren, Washington Irving, Lydia Maria Child. Narratives: Olaudah Equianos The Interesting Narrative of the Lfe of Olaudah Equiano. Novels: Hannah Webster Fosters The Coquette. †¢Romantic Period, 1828-1865 Characteristics The Romantic period covers the period between Jacksonian democracy to the end of the Civil War. This period was the first major explosion of a distinctly American body of literature; for this reason, this period is also referred to as the American Renaissance. Many of American literatures most well-known writers emerged during this time. Readership increased significantly and the 1850s saw a number of immensely popular novels. Issues and subjects addressed in the literature of this time ranged from the American identity, to the slavery debate, to historical narratives, to poems and narratives inspired by romanticism, to prose works examining national unity. Major Writers or Works Poetry: Henry Wadsworth Longfellow, Lydia Sigourney, Edgar Allan Poe, Walt Whitmans Leaves of Grass, Emily Dickinson. Prose: Edgar Allan Poe, Nathaniel Hawthorne, Rebecca Harding Davis, William Lloyd Garrison. Narratives: Frederick Douglass, Harriet Jacobs Incidents in the Life of a Slave Girl. Novels: James Fenimore Cooper, Nathaniel Hawthorne, Catharine Maria Sedgwick, Herman Melville, Susan Warner, Maria Susanna Cummins The Lamplighter, Harriet Beecher Stowes Uncle Toms Cabin, William Wells Brown, Harriet E. Wilson. Drama: George Aikens play, Uncle Toms Cabin, based on Stowes novel. †¢The Age of Transcendentalism, 1836-1860 Characteristics Transcendentalism, though varied, investigated the relationship between nature, humanity, society, and the divine. Major Writers or Works Prose: Ralph Waldo Emersons Nature, Self-Reliance, and The American Scholar, Margaret. Fullers Woman in the Nineteenth Century, Henry David Thoreaus Walden, Bronson Alcott. †¢Realism, 1865-1900 Characteristics The post-Civil War period was an era of increased industrialization and urbanization as the nation attempted to recover emotionally, culturally, and politically from the aftermath of the war. Though there were still elements of romanticism, this period was considered realistic in its emphasis on unidealized and truthful depictions. Major Writers or Works Poetry: Walt Whitman, Paul Laurence Dunbar, Emily Dickinsons poems published posthumously. Prose: Sarah Orne Jewett, Mary E. Wilkins Freeman, Zitkala-Sa, Charlotte Perkins Gilmans The Yellow Wallpaper, George Washington Cable, Kate Chopin. Novels: Mark Twains The Adventures of Huckleberry Finn, William Dean Howells, Bret Harte, Louisa May Alcotts Little Women, Henry James, Helen Hunt Jacksons Ramona, Frances E. W. Harpers Iola Leroy. †¢Naturalism, 1900-1914 Characteristics An offshoot of realism, naturalism claimed to give an even more realistic and unflinching depiction of contemporary life. Naturalism was characterized by a pessimistic view of humanity and human existence. Major Writers or Works. Prose: Frank Norris, Jack London, Stephen Crane, Hamlin Garland. Novels: Frank Norris McTeague, Theodore Dreisers Sister Carrie, Jack Londons The Sea-Wolf, Stephen Cranes Maggie: a Girl of the Streets. †¢Modern Period, 1914-1939 Characteristics A period in British and American literature spanning the years between WWI and WWII. Works in this period reflect the changing social, political, and cultural climate and are diverse, experimental, and nontraditional. Major Writers or Works Poetry: Robert Frost, Carl Sandburg, Wallace Stevens, William Carlos Williams, T. S. Eliot, Edna St. Vincent Millay, e.e. cummings, H. D. Novels: Edith Wharton, Willa Cather, Sherwood Anderson, John Dos Passos, F. Scott Fitzgerald, William Faulkner, Sinclair Lewis, John Steinbeck, Ernest Hemingway. Drama: Eugene ONeills. The Emperor Jones, Susan Glaspells, Trifles, Clifford Odets. †¢Harlem Renaissance, 1920s and 1930s Characteristics The Harlem Renaissance was the first major burgeoning of visual, literary, and performing arts by African Americans concerned with African-American life, art, culture, and politics. The influence of the Harlem Renaissance remained strong for the remainder of the 20th century. Major Writers or Works Poetry: Langston Hughes, Countee Cullen, James Weldon Johnson, Claude McKay. Prose: W. E. B DuBois, Jean Toomer. Novels: Zora Neale Hurston, Nella Larsen, Passing, Jessie Redmon Fauset, James Weldon Johnson, Claude McKay. Drama: Randolph Edmonds, Langston Hughes. †¢Lost Generation, 1920s Characteristics After WWI, a group of American writers grew increasingly disillusioned by, and resistant to, what they saw as hypocrisy in dominant American ideology and culture. Many of these writers left America in search of a more artistic life in London or Paris. Major Writers or Works. Poetry: Ezra Pound, T. S. Eliot. Prose: Gertrude Stein, T. S. Eliot. Novels: F. Scott Fitzgerald, Ernest Hemingways The Sun Also Rises. †¢Beat Writers, 1950s Characteristics Beat Writers writing was generally anti-traditional, anti-establishment, and anti-intellectual. Major Writers or Works Poetry: Allen Ginsbergs Howl, Lawrence Ferlinghetti. Prose: Gertrude Stein, T. S. Eliot. Novels: William Burroughs, Jack Kerouacs On the Road. †¢Postmodern or Contemporary, 1940-present Characteristics In British and American literature, the postmodern period refers to literature written after WWII. The postmodern period reflects anxieties concerning, and reactions to life in the 20th century. Postmodern works are often highly experimental and anti-conventional. Major Writers or Works Poetry: Sylvia Plath, Marianne Moore, Robert Penn Warren, Anne Sexton, Gwendolyn Brooks, Adrienne Rich, Philip Larkin. Prose: Eudora Welty, Raymond Carver, John Cheever, Alice Walker. Novels: Saul Bellow, Ralph Ellison, John Updike, Kurt Vonnegut, Jr. , Richard Wright, Thomas Pynchon, E. L Doctorow, James Baldwin, Toni Morrison. Drama: Edward Albee, Arthur Miller, Tennessee Williams, Lorraine Hansberry, August Wilson, David Mamet.

Sunday, October 27, 2019

N. Fowleri Diagnosis, Treatment and Prevention

N. Fowleri Diagnosis, Treatment and Prevention Historical Aspect: Naegleria Fowleri (N. Fowleri ) is a free living, thermophilic protozoan that is a human specific pathogen that attacks the central nervous system. It can be found in contaminated freshwater sources. It enters through the nose and travels to the brain causing primary amoebic meningoencephalitis1. It was first observed in 1899 and later named after Dr. M. Fowler, who observed the first reported fatal cases of acute pyogenic meningitis in Australia in 19652. While these infections have been identified as early as the 19th century it is challenging to identify because it mimics many of the symptoms of bacterial meningitis[1]. Primary amoebic meningoencephalitis (PAM) is a necrotizing and hemorrhagic meningoencephalitis3. The symptoms begin 1-9 days after the onset of infection these symptoms include fever, nausea, headache and vomiting. The initial symptoms mimic those of bacterial meningitis, the later symptoms are unique to this disease. Later symptoms include neck stiffness, hallucinations, seizures, an inability to focus, lack of balance and eventually coma and death. The mortality rate for this disease is 95%. The disease progresses quickly and leads to death within 12 days of the initial infection1. While this infection has a high mortality rate, it is very rare. There have been 300 reported cases of PAM worldwide in the last 40 years4. It is important to note that this conditioned is often misdiagnosed so these numbers are estimates. In the United States there have been 138 cases in the last 50 years1. This infection was once a condition that plagued developing countries but the incidence is spreading all over the world. Researchers suspect that the increased temperatures due to global warming, increased use of public water sources due to scarcity and an overall increase in aquatic recreational activities are to blame3,18. While swimming and other aquatic recreational activities help proliferate this disease so do rituals. Aga Khan University in Pakistan noticed an increased number of deaths caused by PAM in young males that had no history of swimming, but were devout Muslims. Those who practice this faith pray five times a day and before every prayer, they perform ablution, ablution is the washing of the hands, face, ears, nose, mouth, arms and feet. While cleansing the nose, water is forced up the nose putting individuals performing this practice with inadequately purified water at a greater risk for PAM3. Religious festivals like the Kumbh Mela where Hindus gather and swim in the Ganges river put those who participate at risk of developing diseases like PAM caused by N. Fowleri 3. In addition to religious practices, therapeutic interventions like the Neti pot increase the risk of PAM. Nasal irrigation systems like the Neti pot work to relieve the symptoms of sinusitis and cold. It works by removing debris and mucus from the nasal passages. The recommendation is that the water should be boiled or mixed with a non-ionized sodium chloride. Basic structure: N. Fowleri are a part of the free living amoeba that cause infections in the central nervous system. Some of the other protists are Acanthamoeba spp and Balamuthia mandrillas. Naegleria fowleri have been classified by modern techniques which analyze morphology, biochemical pathway and molecular phylogeny2. The modern approach classifies N. Fowleri as a part of the super group Excavata, in the group Heterolobosea and a part of the family Vahlkampfiidae. Although the genome for N. Fowleri is not yet completed there are some studies producing information about its molecular and genetic characteristics. N. Fowleri s genus includes more than 40 species, but N. Fowleri is the only one that is known to cause disease in humans. De Jonckheere created the most popular identification system for N. Fowleri . The identification system uses genetic markers like internal transcribed spacers (ITS1) and 5.8S rDNA 2. This identification system revealed at least 8 different genotypes. The genotypes are dispersed among different continents America (I,II,III), Europe (III,IV,V,VI,VIII), Oceania (V), and Asia (II,III). Of the eight genotypes only four have been found in humans, types 1-42. Naegleria are a part of the group heteroloboseans that have a three-phased lifecycle. They are first amoeba, then flagellate and lastly cyst formation5. N. Fowleri reproduces in the amoeba form via binary fission to produce the cyst and the flagellate forms. The entire cell cycle is 8 hours, N. Fowleri spends 28 minutes in M phase, 180 minutes in G1, 183 minutes in S phase, and 90 minutes in G22. In the amoeba form, the trophozoite ranges in size from 15-25 Â µm. Trophozoites also have cytoplasmic projections called food cups which allow phagocytosis of bacteria, yeast, erythrocytes and cellular waste. Trophozoites are the form of the amoeba that can feed and divide, they are also the form that enter the human host6.Trophozoites will transition into the flagellate stage after being exposed to a saline solution2. The flagellates cannot feed or divide, the transition also involves a change in shape from pleomorphic to pear shaped with a pair of flagella. The flagella have the typical 9+2 structure and are surrounded by a cytoplasmic membrane. The 9+2 flagella structure describes the cross- sectional arrangement of microtubules that make up the flagella. There are nine doublet outer tubules and two central singlet tubules7. The cyst form is resistant to most disinfection. The cyst formation is spherical, smooth, double walled and refractive. They measure about 20Â µm. The material of the cyst wall is synthesized and packaged by the rough endoplasmic reticulum2. Route of Transmission: N. Fowleri is a thermophilic amoeba, its optimal temperature ranges from 1150 to 1220 F. N. Fowleri can typically be found in warm freshwater like lakes and rivers, warm water from industrial parks, or inadequately chemically treated water, other warm water sources like water heaters and soil. In their natural environment N.Fowleri phagocytize cyanobacteria and eubacteria to regulate levels. Samples from the lakes of the southern United States reveal that N. Fowleri introphozoite formis present during the summer. During the winter months N. Fowleri in cyst form survive in freshwater sources, but no form of N. Fowleri can withstand freezing temperatures1 . Most cases of PAM are caused by swimming in warm freshwater, from drinking water, recreational activities, ritual abulation and sinus irrigation systems1. Infection occurs when water containing N. Fowleri gets into the nose. The amoeba enters the nose and travels along the olfactory nerve, through a bony plate in the skull called the cribriform plate3. Once it reaches the brain it causes meningoencephalitis, cerebral edema and results in herniation. The olfactory bulbs and orbitofrontal cortices become necrotic and hemorrhagic. The data on both humans and mice support the conclusion that death is ultimately caused by increased intracranial pressure and herniation3. Swimming in water containing N. Fowleri increases the risk for PAM but age and sex are also risk factors. From the 1962- 2015 there have been 138 reported cases of PAM in the United States, 114 of the cases have been children around the age of 12. Nearly 75% of the infections have affected males1. Certain behaviors are associated with an increased risk of infection, those infected individuals reported participating in water related activities like swimming, diving and head dunking1. Although N. Fowleri can be transmitted through water it cannot be transmitted through aerosols or droplets, or via person to person contact. N. Fowleri can be found in other organs of the body, such as the heart, lung, spleen and thyroid1. Pathogenesis: N. Fowleri enter the human host through the nose which provides access to the brain. Within eight hours of infection N. Fowleri is present in the mucus layer of the olfactory epithelium. Within 24 hours N. Fowleri are in the olfactory bulb and present in the cribriform plate. By 96 hours neutrophil polymorphs cause a severe inflammatory response in the olfactory bulb which leads to brain tissue damage3. Contact dependent mechanisms are N. Fowleri mediated pathogenic processes. The primary mechanism of pathogenesis in N. Fowleri is adhesion. Adhesion allows for movement and chemotaxis in the nasal mucosa and assists N. Fowleri with disease progression. Adhesins are expressed on the surface of N. Fowleri, the adhesins are integrin like proteins surrounded by adhesion like structures. Fibronectin binding protein, protein kinase C and NFa1 are important to interrupting the host mediated cytotoxicity3. In an experiment testing cytopathicity of N. Fowleri, a culture would bind to Fibronectin and in the presence protein kinase C the ability of the amoeba to adhere increased8. N. Fowleri also produces Reactive Oxygen Species (ROS) which damage the host cell. Following cell damage, N. Fowleri uses phagocytosis and amoebastomes to assist N. Fowleri in breaking down and consuming the cells through a sucker structure on its surface. These processes are mediated via actin and involve the polymer ization of monomeric G-actin and filamentous F-actin. Studies have found that a membrane protein Mp2CL5 may also play a role in pathogenicity, without this protein N.Fowleri are nonpathogenic3 .This protein is suspected to aid in pathogenicity by navigating the environment, and movement toward food sources9. In addition to contact dependent mechanisms of pathogenicity, N.Fowleri also utilizes contact independent mechanisms. N-PFP is a cytolytic pore forming protein that depolarizes the cell membrane and decreases the integrity. Naegleriapores A and B are pore forming polypeptides that are very similar in structure and function. Both are antimicrobial and cytolytic polypeptides3. The enzymes phospholipase A, A 2 and C are present in patients with PAM. Phospholipases are responsible for the demyelination of white matter. Sphingomyelinase, neuroaminidase, elastase and proteolytic enzymes are responsible for demyelinating nerve tissue. N. Fowleri are hemolytic due to the heat shock protein 70 which is unaffected by salt concentrations, chelating agents, pH and temperature extremes3,10. This protein is present in the cytoplasm, pseudopodia and phagocytic food cups. There are many other factors associated with the pathogenicity of N. Fowleri and others that are suspected to have an effect on t he pathogenicity. On the onset of infection the hosts innate immune system attempts to reduce the pathogens cytotoxicity. During the early infection the body releases mucin which surrounds the N.Fowleri trophozoites to prevent cytotoxicity. In the later infection eosinophils and neutrophils surround the N. Fowleri cells to prevent cytotoxicity. Inflammation increases over time, although there are not many cells that penetrate the host epithelium. The inflammation and polymorph nuclear cells from the host response damage cerebral tissue2 . Diagnosis, Treatment, Prevention: Diagnosis of N. Fowleri is heavily dependent on laboratory techniques. The most effective way to diagnose N. Fowleri requires cerebrospinal fluid (csf) which is conducted while the patient is living and brain biopsy which is conducted post-mortem11. Different laboratory tests are utilized to analyze the specimen. When PAM is suspected, samples can be wet mounted and placed under a microscope to identify trophozoites12. Polymerase chain reaction is a method that can be used to amplify DNA, to identify the presence of N. Fowleri DNA in a sample11. Another laboratory technique involves antigens that were developed from mouse monoclonal antibodies (mAbs) against N. Fowleri . When indirect immunofluorescence assays are used mAbs react to N.Fowleri from specific geographic regions13. The infection due to PAM progresses quickly and as previously stated, mimics symptoms of bacterial meningitis. Even with the advances in laboratory diagnostics most cases are diagnosed post mortem making effective treatment elusive. One successful case study provides an example of effective diagnosis and treatment of this condition. On July 13, 2013, a 12 year-old girl presented to Arkansas Childrens Hospital vomiting, having trouble holding up her head and was unable to open her eyes. A few days prior to hospitalization the patient had been playing in a local water park. During her hospitalization she experienced hallucinations, and thirst. A spinal tap was performed which ruled out bacterial meningitis. The laboratory identified N. Fowleri trophozoites in the patients cerebrospinal fluid. After determining the infection was PAM caused by N. Fowleri, physicians initially treated the patient with antibiotics and antifungals like Amphotericin B, Rifampin, Fluconazole, Dexamethasone an d Azithromycin .None of these treatments improved the condition of the patient. The hospital petitioned the Center for Disease Control (CDC) to allow the use of a new experimental drug available for the treatment of N.Fowleri14. The drug Miltesfosine was given 36 hours after the initial diagnosis, physicians also lowered the patients body temperature to 93.2 F0 to reduce cerebral edema and intracranial pressure. After 18 days in the ICU there was no N. Fowleri found in her system. The patient experienced a full but gradual recovery over the next fifty five days. After seven days the patient was able to write her name, in fourteen days she was able to speak in one and two syllable words. She also underwent both speech and physical therapy14. This patient is one of the three known survivors of PAM. While the virulence factors and the degree of recovery that surround the other two cases of survival are unknown. The prompt diagnosis, treatment with Miltesfosine within thirty six hours and maintaining a low body temperature for this patient played significant roles in effectively treating this infection14. Although the first case of N. Fowleri was over 50 years ago, the mortality rate for this disease continues to increase due to water scarcity which increases use of water from public sources. As previously stated this condition is either diagnosed post mortem or misdiagnosed. The development of a standard microbial treatment will aid in the reduction of high mortality rates14. In the three cases of survival the patients were all intially treated with amphotericin B, rifampcin, fluconazole, dexamethasone and phenytoin during the first week of infection15. In 1969 a patient survived PAM with the successful treatment of amphotericin B. The patient in 2013 was initially treated with amphotericin B and it was ineffective. Miltesfosine effectively treated this patients PAM14. Other drugs with the potential to treat PAM have been tested, and some have been proven effective while others have not. Clotrimazole a drug that has been used as an antifungal had potential to treat PAM but under further study was deemed ineffective16. In developing countries like Pakistan where water is in short supply and ablution is common practice the danger of becoming infected with N. Fowleri is greatly increased. Water sources in these countries include wells or water storage tanks which are often contaminated with N. Fowleri 17. In order to prevent infection the World Health Organization (WHO) encourages that water storage units and wells be regularly tested to ensure proper disinfection. Public health organizations have also encouraged the use of nose clips while swimming in lakes and other freshwater sources, and boiling water that is used for ablution17. Chlorine disinfection regimens prevent against most pathogens in drinking water systems however free living amoeba like N. Fowleri survive most disinfection. The cyst form of N. Fowleri is resistant to most disinfection and are associated with biofilm that can build up in drinking water systems. N. Fowleri have been isolated in drinking water systems in Australia, the United States and Pakistan, in both Australia and the United States they maintain chlorine levels of 0.5mg/L at all times in the drinking water18.To test the amount of chlorine needed to eliminate N. Fowleri, researchers conducted an experiment using two separate sites, a pre re-chlorination site and a post re-chlorination site, both sites were monitored before and after re-chlorination for a year. The results were that after chlorination of greater than 1mg/L at each site, in the post re-chlorination site the amoeba were gone within 60 days. The pre re-chlorination site would have seasonal flares of N.Fowleri but the c hlorine levels eliminated the protozoan and prevented further spread. Overall chlorine levels above 1mg/L result in the elimination of N.Fowleri in drinking water systems18. Summary of current areas of research notes: N. Fowleri is a rare pathogen that was discovered over fifty years ago. Since its discovery still not much is known about this pathogen. Future research into this pathogen will focus on patient complaint diagnosis and treatment, expanding the drugs that are used, biomarkers, and drug targets. In order to determine whether the patient has contracted PAM due to N.Fowleri the patients csf is tested and if the test is negative for bacterial cultures and the patient has a history of swimming or other aquatic activities, then the patient tests positive for N.Fowleri. Extracting csf can increase the pressure in the patients brain and lead to herniation of the brain. Because N. Fowleri travels to the brain via the nasal passage, the proposed route of diagnosis is collecting a nasal sample. Research confirms that N.Fowleri can be collected in both csf and nasal cultures3. Drugs administered through the nasal cavity, through the transcribial route would be delivered across the cribifrom plate to the inferior portion of the frontal lobe. This is the site where N. Fowleri attacks and spreads to the central nervous system. Drugs like amphotericin B do not decrease the minimum inhibitory concentration (mic) when administered intravenously. By potentially administering the drug transcribialy, the drug passes the blood barrier which would allow the drug to be more potent, trail the route of N.Fowleri, attack the site of infection, allow the lethal dose of drug to achieve the mic without venous drainage, and lastly to avoid symptoms of intravenous drug administration 15. There are clinically approved drugs that have promising amoebicidal effects. These drugs interrupt the mechanisms and processes of the amoeba. Digoxin and proyclidine both exhibit amoebicidal properties. Digoxin treats atrial fibrillation and heart rhythm disorder by helping the heart beat stronger and with more rhythm19. Proyclidine is used to treat Parkinsons and other diseases that cause involuntary muscle movement20. In order for further testing of the amoebicidal effects of these drugs to continue to be studied more drugs that have the potential to be amoebicidal must be identified and screened for tests to go from in vitro testing to in vivo testing. There has not been a lot of emphasis on finding drugs that treat N. Fowleri because the condition is rare and affects populations in the developing world. Biomarkers for PAM have been challenging to identify because little is known about N. Fowleris pathophysiology. Mass spectrometry, NMR and other tools of analysis are being utilized to identify biomarkers. Researchers are also making biochemical profiles of individuals in populations that contracted the disease against those who did not. These profiles will include information on the individuals age, gender, ethnicity and factors that predispose them to this condition3. This condition is rare and because of its rarity has been studied infrequently. With limited time and resources N.Fowleri is funded and studied less frequently than conditions that affect larger populations like Malaria or the Zika virus. The range of drugs used to treat patients with PAM is severely limited, researchers are developing drugs that would inhibit different processes of N.Fowleri. The drug pathways are hydrolytic enzymes that invade the host cells, glycocytic enzymes that are expressed differently by the pathogen, thiol based redox metabolism pathway, oxidative stress pathway, trypanothione pathways, and encystation and excystation pathways3. Bibliography 1. Naegleria fowleri- primary amebic meningoencephalitis (PAM) amebic encephalitis. Centers for Disease Control and Prevention Web site. =. Updated December 2015. Accessed January, 2017. 2. Martinez-Castillo M, Cardenas-Zuniga R, Coronado-Velazquez D, Debnath A, Serrano-Luna J, Shibayama M. Naegleria fowleri after 50 years: Is it a neglected pathogen? J Med Microbiol. 2016. doi: 10.1099/jmm.0.000303 [doi]. 3. Siddiqui R, Ali IKM, Cope JR, Khan NA. Biology and pathogenesis of naegleria fowleri. Acta Trop. 2016;164:375-394. doi: http://dx.doi.org/10.1016/j.actatropica.2016.09.009. 4. Coupat-Goutaland B, RÃ ©goudis E, Besseyrias M, et al. Population Structure in Naegleria fowleri as Revealed by Microsatellite Markers. Chiang T-Y, ed. PLoS ONE. 2016;11(4):e0152434. doi:10.1371/journal.pone.0152434. 5. The genome of naegleria gruberi illuminates early eukaryotic versatility. Cell. (- 5):- 631. doi: 10.1016/j.cell.2010.01.032. 6. Marciano-Cabral F, Cabral GA. The immune response to naegleria fowleri amebae and pathogenesis of infection. FEMS Immunology Medical Microbiology. 2007;51(2):243-259. doi: 10.1111/j.1574-695X.2007.00332.x. 7. Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Section 19.4, Cilia and Flagella: Structure and Movement. Available from: https://www.ncbi.nlm.nih.gov/books/NBK21698/ 8. Han, KL., Lee, HJ., Shin, M.H. et al. Parasitol Res (2004) 94: 53. doi:10.1007/s00436-004-1158-9 9. RÉVEILLER FL, SUH S, SULLIVAN K, CABANES P, MARCIANO-CABRAL F. Isolation of a unique membrane protein from naegleria fowleri. J Eukaryot Microbiol. 2001;48(6):676-682. doi: 10.1111/j.1550-7408.2001.tb00208.x. 10. Song, KJ., Song, KH., Kim, JH. et al. Parasitol Res (2008) 103: 313. doi:10.1007/s00436-008-0972-x 11. Cope JR, Ali IK. Primary amebic meningoencephalitis: What have we learned in the last 5 years? Curr Infect Dis Rep. 2016;18(10):31-016-0539-4. doi: 10.1007/s11908-016-0539-4 [doi]. 12. Baig AM, Khan NA. Tackling infection owing to brain-eating amoeba. Acta Trop. 2015;142:86-88. doi: 10.1016/j.actatropica.2014.11.004 [doi]. 13. Pugh JJ, Levy RA. Naegleria fowleri: Diagnosis, pathophysiology of brain inflammation, and antimicrobial treatments. ACS Chem Neurosci. 2016;7(9):1178-1179. doi: 10.1021/acschemneuro.6b00232 [doi]. 14. Heggie TW, KÃ ¼pper T. Surviving naegleria fowleri infections: A successful case report and novel therapeutic approach. Travel Medicine and Infectious Disease. . doi: http://dx.doi.org/10.1016/j.tmaid.2016.12.005. 15. Baig AM, Khan NA. Novel chemotherapeutic strategies in the management of primary amoebic meningoencephalitis due to naegleria fowleri. CNS Neuroscience Therapeutics. 2014;20(3):289-290. doi: 10.1111/cns.12225. 16. Jamieson A. Effect of clotrimazole on naegleria fowleri. J Clin Pathol. 1975;28(6):446-449. 17. Siddiqui R, Khan NA. Primary amoebic meningoencephalitis caused by naegleria fowleri: An old enemy presenting new challenges. PLoS Negl Trop Dis. 2014;8(8):e3017. doi: 10.1371/journal.pntd.0003017 [doi]. 18. Miller HC, Morgan MJ, Wylie JT, et al. Elimination of naegleria fowleri from bulk water and biofilm in an operational drinking water distribution system. Water Res. 2016;110:15-26. doi: S0043-1354(16)30912-5 [pii]. 19. Dawson AH, Buckley NA. Digoxin. Medicine. 2016;44(3):158-159. doi: http://dx.doi.org.proxy.campbell.edu/10.1016/j.mpmed.2015.12.006. 20. Procyclidine. Drugs.com Know more. Be sure Web site. https://www.drugs.com/cdi/procyclidine.htm. Updated 2017. Accessed 5/25/17, 2017. [1] Naegleria fowleri- primary amebic meningoencephalitis (PAM) amebic encephalitis. Centers for Disease Control and Prevention Web site. https://www.cdc.gov/parasites/naegleria/pathogen.html#history. Updated December 2015. Accessed January, 2017

Friday, October 25, 2019

The Endless Circle in William Faulkners Barn Burning :: Barn Burning Essays

The Endless Circle in William Faulkner's Barn Burning      Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   William Faulkner's short story â€Å"Barn Burning† is the tale of a southern man forced into a role by society.   â€Å"Barn Burning† takes place in the post Civil War South where a mans place in society is derived by their actions during the war.   Ab Snopse, a man who served both the North and the South, is plagued with his non-allegiance and failure to accept authority.   When Ab comes into conflict with his employer, he finds himself taking control from the authority figure, and reverting back to his mercenary ways.   Having no allegiance, Ab makes the move from helping hand to the enemy by burning down barns.      Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Along with many of Faulkner's short   stories, â€Å"Barn Burning† is set in the imaginary Mississippi county of Yoknapatawpha.   During the restoration of the South, the time period following the Civil War, the only thing that kept the South alive and running where the memories of fallen heroes and the belief that the South would someday regain the status that it had once held.   Families like the Sartorises and the de Spains were glorified and praised for honors that their family members had achieved during battle.   The honor that families like these were granted placed them in public offices, and gave them opportunities to prosper where others could only dream about.   This same honor seemed to carry on to those who shared the names of the great war heroes.   â€Å"‘Hey', the Justice said. ‘Talk louder. Colonel Sartoris?   I reckon anybody named for Colonel Sartoris in this county can't help but tell the truth, can they?'† (Kennedy 163).      Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   On the other hand, the Snopses are viewed as dishonorable.   During the war, Ab Snopse was considered a mercenary for serving both sides of the way.   â€Å" ...nights passed during those four years in the woods hiding from all men, blue and gray, with his strings of horses (captured horses, he called them)† (165). Ab stole horses from the North and the South, to earn a living.   He was even shot by a confederate soldier, â€Å"His father turned, and he followed the stiff black coat, the wiry figure walking a little stiffly from where a Confederate provost's man's musket ball had taken him in the heel on a stolen horse thirty years ago...†(164). Actions like these caused the community to look down upon the Snopses, which in turn caused Ab to invoke revenge upon his adversaries.      Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   When Ab comes into conflict with an employer, he reverts to his old Civil War ways of non allegiance to benefit himself.

Thursday, October 24, 2019

AP U.S History Essay

When one reviews American History from 1785-1850, it can be concluded that, â€Å"Americans never learned to add without also dividing†. This is referring to America’s inability to have more land without also having the land divided into sections, whether it be north and south or east and west. For example when the Louisiana Purchase was made, yes it added more land to the U.S, but it also made it so there was another territory that was different than the rest of America. The Missouri Compromise can be an example as well, when they applied to become a state, it was being considered however James Tallmadge Jr. introduced an amendment that created a rift being those who were pro slavery and against it. When you look at American history between 1785-1850, it can be said that America can never add without dividing; this statement is correct in saying that and it can be backed up with the effects of the Louisiana Purchase and the Missouri Compromise, which included divisions of the ideas and people, as examples. You can use the Louisiana Purchase to support the argument because, when it was made, although it added more land to the U.S, it also made it so there was another territory that was different than the rest of America as an after effect. When this purchase was finalized it meant more land for the Americas but unfortunately more division within America. Most cities involved in this purchase, like New Orleans can be used as example. In New Orleans, the population was mostly French or Spanish speakers but the rest of the country spoke English. It was also a Catholic city that was engulfed in a country of Protestants, and even furthermore, the ideas of these people about things like race and sexuality differed than those of the rest of the countries. All of these are examples of how cities involved in the Louisiana Purchase differed from the rest of America and supports that even though it was extra land for America it was also divided by the differences it had with America that kept it separate from America. The Missouri Compromise can be used as an example because when it was made, an amendment was also introduced which required slaves to be freed and not added. This amendment caused an uproar within the southern representatives and senators who were  pro slavery. Which further divided the ideas of slavery, whether it be for or against it. Like the Louisiana Purchase, the Missouri Compromise also shows how America can never add without dividing, because, when Missouri was gained as a state it was also introduced that slavery not be permitted there. This divided those who were in favor of it and those who were against it. Which is an example of America always adding but also dividing. When one reviews American History from 1785-1850, it can be concluded that, â€Å"Americans never learned to add without also dividing†. This is referring to America’s inability to have more land without also having the land divided into sections, whether it be north and south or east and west or pro and against. When you look at American history between 1785-1850, it can be said that America can never add without dividing; this statement is correct in saying that and it can be backed up with the effects of the Louisiana Purchase and the Missouri Compromise, which included divisions of the ideas and people, as examples. When the Louisiana Purchase is an example that supports this because land was acquired but divisions was made between them and the rest of America keeping it from being on country under one idea. The Missouri Compromise can be an example as well because when acquired as a state, Tallmadge Jr. introduced an amendment that created a rift being those who we re pro slavery and against it.

Wednesday, October 23, 2019

Glass Castle Essay

However, there are some far more substantial themes and symbols taking place within the novel. These themes require a little more critical thought, and aren’t directly delivered to the reader. One of these themes being the heavy emphasis placed on the glass castle, and also metaphorically what it signifies to Jeanette and her father, Rex. Through extensive deliberation and thought, the meaning of the glass castle becomes clear. It stands for the contrast between how Jeanette views her father, and how everyone else sees him. The idea of the glass castle in itself is the idolized version of Rex that Jeanette sees, while the reality of it never being completed, represents the views that everyone else has. Throughout the novel there are multiple instances that show the strong love and trust Jeanette feels for her father. A bond that remains strong, even when other member’s of the family have lost some of that trust. This contrast of emotions can best be described through various quotes given throughout the novel. â€Å"In my mind, Dad was perfect, although he did have what mom called a bit of a drinking situation† (Walls 23). This is one of the first occasions where the reader is introduced to the contrasting feelings about Rex that members of the Walls family have. Jeannette, despite already knowing that her father has a drinking problem at a young age, still feels that her father can do no wrong. This sets the scene for how most of the book develops, Jeannette idolizing her father, despite the slight disdain visibly felt by others. â€Å"We laughed about all the kids who believed in the Santa Clause myth and got nothing but a bunch of cheap plastic toys. Years from now, when all the junk they got is broken and long forgotten,’ dad said, ‘ you’ll still have your stars† (41). This is yet another example of the strong bond developed between Rex and Jeannette. However, it is important to note this quote is delivered at a time when Rex is still in relatively good standings with the rest of the family, besides just Jeannette. On that Christmas, even though he couldn’t provide his children with material gifts, he was still able to deliver a memorable gift, which the children could cherish for the rest of their lives. I swear honey, there are times when I think you’re the only one around who still has faith in me,’ he said. ’I don’t know what I’d do if you ever lost it. ’ I told him I would never lose faith in him. And I promised myself I never would† (78-79). This quote perfectly sums up the relationship Rex had with his daughter. It also further exemplifies th e acknowledged differences between how Jeannette feels about her father, and how the rest of the family feels. Even though Rex has let Jeannette down just as many times as Lori, or Brian, she is still able to somehow see past these faults of Rex’s. Throughout this novel the character’s general feelings on Rex sway dramatically. Even Jeannette’s feelings for her father are tried at some points. Yet through everything that happens she never truly loses faith in her father. Jeannette always maintains a sense of respect and love for Rex, despite the tribulations he has brought the family through. Even up to his last moments on his deathbed, Jeannette’s positive feelings for her father remain strong. This contrasted affection between what Jeannette feels for Rex, and what everyone else thinks, is what the glass castle really signifies.

Tuesday, October 22, 2019

History Notes Essay Example

History Notes Essay Example History Notes Essay History Notes Essay How successful were the labour governments of 1964-1970 in fulfilling their promise to create a New Britain? During 1964 to 1970, The Labour government planned to create a ‘New Britain’ under the leadership of Harold Wilson. The most important successes of the Labour government include education, social freedoms and the freedoms of women. However, the most important failures of labour included its lack of the scientific minds in the party and its failure of large economic and technological advancement. Firstly, the Labour Government had hopes of reviving and advancing the technology in Britain.In their manifesto, Labour stated ‘We shall create a New Britain – mobilising the resources of technology. ’ This can be supported by their development of a Ministry of Technology and an attempt to base government on scientific principles. In which an emphasis was placed on planning, management and professionalism. Socially, there was an advance towards a more m obile, less class-ridden Britain. With the introduction of the Establishment of the Race Relations Board, which aimed to tackle racial discrimination and promote racial equality.Before the Wilson period, Britain was viewed as segregated, however Labour wanted to change this and integrate society more. A success shown by Labour during this period was the attempt to break down the old class barriers. ‘It was a very good time for the arts and many aspects of education, the Open University in particular. ’ This provides information which supports the idea that the Labour governments of 1964–1970 were a success in creating a new modern Britain. As well as the Open University, Labour’s other education policies included; the development of comprehensive schools and the expansion of higher education.Leading on from this, Labour was successful in building upon social freedoms as well. The establishment of the Ministry of Arts under Jennie Lee increased cultural opp ortunities. This provided funding for the Arts Council and British Film Institute. By doing this, they showed concern to broaden cultural opportunities for all. Furthermore, the Wilson years were in many ways seen as successful and creative. ‘It was an era of social and sexual freedom. ’ As Paul Johnson wrote after the 1970 election ‘We no longer terrorise homosexuals. We do not force mothers to bring forth unwanted children into the world.We do not murder by the rope’. This showed signs of liberalisation against; homosexuality, divorce, abortion and the end of hanging. Thus, supporting the view of the Labour Government trying to create a new modern society. On the other hand, it can be seen that the Labour government never lived up to its manifesto promise to create a New Britain. One of the major factors why Labour was unsuccessful was due to its economic failures. Labour had higher tax rates than the Conservative government and the unions wanted to stop the technological advances in industries.Conservative policies of ‘Rising incomes and lower taxes have made possible a spectacular increase in spending on the essentials’ for British people. Another economic problem that arose during this period was Labour’s slowness to bring about devaluation. Devaluation was when the issuing government had mandated that the price of the currency in foreign dollars is lower than it was before. This added to economic problems as a result of inflation remaining high at 12% between 1969–1970. The Labour Government did not succeed in changing the living conditions of the people. Under Conservative rule the living standards of the British people have improved more than in the whole of the previous half-century. ’ This is shown where over 98% of the working population have jobs that have caused the standard of living for people to increase. This differs from Labour’s ideals, where they focused more on social refor ms rather than improving beneficial changes in the country. In addition, Conservatives did not believe the ideas Labour was suggesting about creating a New Britain. Rather they deemed it to be a ‘camouflage aged return to dreary doctrines which have already proved a failure. Also, the doctrine showed no mention of moral issues, because leaders like Wilson and Brown were conservative on such issues. The Conservatives believed what they were offering was an extension of prosperity which their policies had been proven to achieve. In conclusion, the Labour Government did have some successes during this period in creating a New Britain, which was mainly due to the support they were given by the government. The development of a Ministry of Technology put an emphasis on planning, management and professionalism.And, developing education policies, which included the development of comprehensive schools and the expansion of higher education, meant a breakdown of social barriers. However , The Labour Government never fully achieved its successes in creating a New Britain. This was due to the failure of the economic policies such as Labour having higher taxes than the conservatives. And finally, the Conservative fears that implied Labour’s ‘New Britain’ would have meant a return to the ‘dreary’ and failed doctrines of the past Labour Governments.

Sunday, October 20, 2019

ComparingThe Pact and Memoirs of a Geisha essays

ComparingThe Pact and Memoirs of a Geisha essays English I.S.U-The Pact and Memoirs of a Geisha In the novels The Pact, by Jodi Piocoult and Memoirs of a Geisha, by Arthur Golden there is a strong reflection of life and its negative aspects. Not only do both novels involve a female whos life is controlled by those around her, but the girls are also controlled by a desired conception of themselves that they feel they have to achieve. The predominant ideas that exist in both works are those concerned with ones personal will to live a certain way and to achieve goals that are believed to grant success. Both stories involve a female who, through out her life, endures the pain that sometimes comes with the bleak reality of our world. The childhood traumas and the severe pressure exerted upon each of the woman causes them to suffer; However Sayuri, although, she is deprived of her individual freedom, uses her situation to its full potential where as Emily can not deal with the pain and has a mental breakdown. Both Sayuri, in Memoirs of a Geisha and Emily in The Pact suffer through a childhood trauma. Sayuri, begins her life in the small town of Yoroido, Japan, where she lives with her family and knows herself at this time, as Chiyo; her name does not change to Sayuri until years later. Sayuri is dealing with the deterioration of her mother who is ill with cancer, and is preparing for her death, while her father is a quiet, distant man who neither knows Sayuri or her sister, Satsu. It isone afternoon when her father, with out confronting his wife or children makes a deal with a significant man to sell his children. Sayuri is taken to see a lady who inspects her in appalling ways to find out if she is suitable to be sold. Sayuri soon finds herself on a train leaving Yoroido, where she will be separated from her entire family and transported to a far town called Gion. Years later, while being treated as a slave in an Okiya, a Japanese Geisha house in Japan, Sayuri is sti...

Saturday, October 19, 2019

An Analysis of Tone in The Road Not Taken, a Poem by Robert Frost

An Analysis of Tone in The Road Not Taken, a Poem by Robert Frost Robert Frosts work The Road Not Taken conveys a very simplistic, yet introspective theme. The poem describes the dilemmas and choices one must make in life, and how those specific decisions affect that person. Frost establishes this theme with an allegorical illustration of two paths in the woods. Later in the poem, the author reveals the attributes and personality of the main character as he or she contemplates past life choices. This characterization helps to bridge the gap between the reader and the character, allowing the poem to communicate a deeper resonance. Frost strengthens the readers figurative presence in the poem by presenting such emblematic diction and setting. The use of such devices again aid to the connection between the reader and the character-forcing Frosts message to become even more insightful. Robert Frost portrays a very pensive and impactful tone in his poem The Road Not Taken through means of symbolic imagery, representative setting, thorough characterizati on, and powerful diction, in order to encourage the reader to reflect upon his or her own life choices. One of the most significant elements of this poem is Frosts use of imagery. In the opening lines of the poem, the main character stops at a forked path in the forest, pondering which direction he or she will go. This part, being one of the most vital, symbolizes a choice needing to be made, most likely in life. Roads in literature often correlate with travel or a migration from one place to the next. So, the characters consideration about which road to take reveals a self-reflection the character has about which direction to go in life. Secondly, before the character continues his or her journey, he or she notes that the end of the first trail is covered by a sort of undergrowth, metaphorically indicating the perplexity of life and the inability to predict the consequence of life choices. The poem unmistakably exhibits this analysis in the first stanza, Two roads diverged in a yellow wood, / And sorry I could not travel both / And be one traveler, long I stood / And looked down one a s far as I could / To where it bent in the undergrowth (lines 1-5). Furthermore, it can be said that Frosts use of these figurative images are centralized to exemplify his tone of self-reflection and cogitation, as they boldly depict the importance of lifestyle decision-making. Another literary aspect Frost utilizes to express his tone is setting. In the poem, he writes, Two roads diverged in a yellow wood (line 1). The phrase a yellow wood may be an indication of the color the trees radiated. This suggests that the story takes place in the middle of autumn, most likely, contributing to the sense that time is running out-as in life-for the character. Here, Frost again outlines his tone as he demonstrates the characters rational contemplation and, eventually, regret. The author further establishes the setting as he indicates that the paths were not worn, even stating that one was grassy, providing a location of serenity and aesthetic beauty. This rendition of the setting applies a philosophical aspect to the poem, as it represents a life of innocence and potential. The forked trail could symbolize maturation and development, as the character is forced to choose which direction he or she wants to take his or her life. In the second stanza, it states, Then too k the other, as just as fair, / And having perhaps the better claim, / Because it was grassy and wanted wear (lines 6-8). In this part of the poem, it almost seems as if the character foolishly expected life to desire him or her to enter it, as the poem suggests the grass wanted to be worn down. This is probably one of the reasons why the character emotes regret later in the work. Again, Frost communicates his solemn and contemplative tone by familiarizing the reader with the characters experiences. Frost draws the reader into the story as he characterizes the man or woman standing in the woods. The character evidently appears conflicted throughout the story as he or she faces a dilemma and eventually has mixed emotions when one of the options were chosen. As the second stanza begins, the character states that he or she hastily chose the grassy trail which, according to the theme, is not wise. The author seems to suggest that the character is highly impulsive, while also adventurous, considering that he or she is wandering through the forest, almost aimlessly. As the story progresses, however, the character seems to be regretful of the choice he or she has made. For instance, as the character walks, he or she begins to seem fearful that the opposite path may have been more alluring or aesthetic. This becomes evident in the third stanza, stating, And both that morning equally lay / In leaves no step had trodden black. Oh, I kept the first for another day! Yet knowing how way lead s on to way, / I doubted if I should ever come back. (lines 11-15). Understanding the characters feelings again strengthens the relationship between the reader and the character, making the authors reflective tone and solemn message become even more compelling. The final figurative element Frost incorporates into the poem is diction. This becomes prominent in the final stanza, as it reveals the characters regrets. I shall be telling this with a sigh / Somewhere ages and ages hence: / Two roads diverged in a wood, and I-/ I took the one less traveled by, / And that has made all the difference. (lines 16-20). With use of the word sigh, Frost delineates the characters dissatisfaction with his or her choice. In the conclusion of the poem, the character, realizing that he or she had made the wrong choice, suggests that if the other path had been taken, he or she would have made the better choice. This ties in with Frosts tone as it is represented in the characters regrets. Robert Frosts short poem The Road Not Taken proves its literary merit through an intensely developed theme, as well as tone. Frost organizes an exceedingly philosophical and contemplative piece, through use of numerous literary devices. One of the most eminent include metaphorical imagery, such as autumn, a forest, and paths. He further exemplifies the tone as he employs setting and characterization. With these instruments, the poem is able to appeal to the reader, as it seemingly allows an immersion into the text. Finally, the authors application of diction contributes to what makes the text so captivating, as it lets the reader delve into the mind of the character. The poem The Road Not Taken by Robert Frost illustrates an insightful, yet regretful tone through use of setting, characterization, imagery, and diction, for the sole purpose of making the reader aware of the haste and intricacy of life.

Friday, October 18, 2019

Banning packed lunches Research Paper Example | Topics and Well Written Essays - 2500 words

Banning packed lunches - Research Paper Example According to the article on the website of Mother Nature Network (MNN) which first appeared on April 12 this year, the principal of Little Village Academy in Chicago has made a move to ban packed lunches after seeing kids drinking soda and eating junk foods for their lunch. Considering different factors, this initiative by Carmona may be applauded by other school officials who in turn could implement the same policy. Carmona’s observation of children carrying unhealthy foods and beverages is true. It happens in every school, regardless of the children’s economic status. In fact, it is even true at homes. Many parents nowadays allow their kids to eat whatever they like, without thinking of nutritional value simply because they are not home to see what their children are eating, and they themselves have become engrossed with the fastfood nation. The practice of eating processed foods has become a tradition. Many families rely on cooking processed meat in order to save tim e and energy. However, this practice should be stopped right away in order to ensure the health and safety of our young children. At home, parents should monitor what the kids are eating and teach them to take in only those foods which promote good health. Being the second home, schools should take the initiative to care for children and implement the rule made by Carmona. The moment the parents send their kids to school, they are already delegating the responsibility of taking care of their child to school authorities. This means giving full trust to the principal and teachers to decide for the good of the child. Ensuring that children receive the proper daily nutrition they need is one very important aspect of taking care of children. Such role should be ensured in order to secure children’s future. Considering this, Carmona’s move should be implemented in all schools, hence it is high time for school authorities to consider reviewing the said rule. Carmona’s regulation is nothing new. In fact, it is just a response to the state-wide call for health and nutrition. Many nutrition plans have been made beforehand but they still seem to be inadequate especially when it comes to implementation. For instance, according to the website of the Department of Agriculture, the office, with its program called National School Lunch Program, reimburses students’ meals with nutritious after-school meals such as whole wheat bread, meat, milk, and so on. However, this intervention is not preventive of obesity or eating unhealthy foods. According to the Troiano and Flegal (82), the rate of obesity cases among adolescents progressively rises because of eating junk foods. On this note, parents should be alarmed and do their best to teach their kids how to eat healthy foods. However, instead of promoting healthy eating, parents are the ones who tolerate and teach their kids to eat unhealthy foods by preparing fancy lunches such as nachos, desserts, pac ked with soda or other energy drinks. Recognizing the current problem, Principal Carmona is doing a good job, imposing the banning of packed lunches. If parents cannot satisfy the nutritional needs of their children, this is their chance to give nutritious food without too much effort. With a small amount, kids can take advantage of healthy snacks and lunches composed of fresh fruit, drinks, and potatoes. Served at the school canteen, parents can also be assured that the foods are prepared carefully. Nutrition is also ensured as school officials themselves monitor what the

Improving Parent-Educator Relationships for Rural Special Education Essay

Improving Parent-Educator Relationships for Rural Special Education - Essay Example But the authors emphasize that it is not yet too late for them to work in increasing the awareness level of parents. To ensure that the roles of both sides are clearly delineated, teachers must take the initiative in being sensitive about the structure of special education teams and in reaching out to the parents. In holding parent-educator meetings, time and place is a crucial factor; such meetings should allow the two parties to work together and interact in a common venue. Conclusion Effective special education programs are the result of the collective efforts of all stakeholders. Without parents in the circle, educators and members of the larger community will not be able to develop authoritative special education intervention programs since these lack ‘humanness,’ with no bases on real-life experience. In the rural setting, since parents are on the underprivileged side, educators and other special education professionals are supposed to go the extra mile in making t hem involved in developing strategies for educating special children. The article reviewed has clearly articulated the abovementioned message. Since this is more of a survey of previous literature, it is suggested that future studies concentrate on the erring side, the educators, for a fairer assessment of the whole special education process. Using a multi-method approach (i.e., employing both qualitative and quantitative research methods) will help generate reliable information regarding the respective roles of teachers and parents in providing quality education for special children, as well as in applying intervention strategies to help such children cope with the learning environment. Reference Trussell, R.P.,... This essay analyzes that effective special education programs are the result of the collective efforts of all stakeholders. Without parents in the circle, educators and members of the larger community will not be able to develop authoritative special education intervention programs since these lack ‘humanness,’ with no bases on real-life experience. In the rural setting, since parents are the underprivileged side, educators and other special education professionals are supposed to go the extra mile in making them involved in developing strategies for educating special children.The article reviewed has clearly articulated the above-mentioned message. Since this is more of a survey of the previous literature, it is suggested that future studies concentrate on the erring side, the educators, for a fairer assessment of the whole special education process. Using a multi-method approach will help generate reliable information regarding the respective roles of teachers and pare nts in providing quality education for special children, as well as in applying intervention strategies to help such children cope with the learning environment. With the rise in the number of special children in general education classes, today’s teachers are confronted with the challenge of meeting the needs of such exceptional students. From this realization, Jenkins and Yoshimura (2010) demonstrated how professional development will play an integral role in helping teachers acquire basic knowledge and skills in special education.

The Traditional Pedagogical Method of Learning Assignment

The Traditional Pedagogical Method of Learning - Assignment Example Teachers have to provide motivation and further encourage the student to continue exploring and questioning the matter. It is important for the students to learn to apply what the teacher has delivered as information. This educational goal can be achieved if they learn how to think abstractly. The teacher has to equip them with the tools to critically evaluate situations and problems and then determine by themselves the solution. This happens when the teacher uses strategies and concepts that build skills required for productive collaboration. Students have to construct their own meaning despite the directions and teaching methods of the teachers (Science for all Americans 1990). Through the principles of learning and teaching, the learning environment also encourages students to develop their independent and interdependent learning abilities. The teachers should establish an atmosphere where the students can learn both individually and with each other. Such tasks can be beneficial especially for young students who still orient themselves in the educational setting. Learning usually occurs when students have the opportunity not only to express their ideas but also to get feedback both from their peers and teachers (Science for all Americans 1990).

Thursday, October 17, 2019

Anthropology Essay Example | Topics and Well Written Essays - 750 words - 9

Anthropology - Essay Example The cuts that congress has put on the food stamp program are oppressive to those individuals who rely on this program to ensure that they make their ends meet (Wallbank). Because of the cuts that have been instituted, it will make it much harder for individuals to ensure that they keep their families well fed, and it is a fact that many of the people who rely on this program might end up going hungry. It can be said that if one were to consider this according to the Marxist principle, one will find that Congress, many of whose members are well off members of the society, is making an attempt to maintain the current status quo through denying the poor a means through which they can be able to improve their lives. The current social and economic institutions as they exist in American society have suited the needs of the elite within this society and this is the reason why many of the latter would like it to remain as it is. The cuts of finding can be considered to be a relationship between the elite and the masses who are involved in the economic process and the best example that can be stated of this concept is related to the concept of a correlation between a master and a slave. It is a familiar Marxist belief that the economic structure of a society has an effect on its political structure, and as such, the elite, being the one who run the economy, have the power to ensure that they influence every aspect of the lives of the people within the society. The fact that Marxists are all in accord that social class has a direct effect on the economy is fundamental because it shows how societies develop within their own contexts (Ouyang 643). In the long run, it is the elite which benefits because they are the ones who will get the services derived from the money that is saved. The large corporations have come to dominate the globe in a variety of ways that cover the entire social life of societies. It is a fact that the corporations which have a global influence

Assignment Essay Example | Topics and Well Written Essays - 250 words - 14

Assignment - Essay Example This allows each department to focus on one task, allowing the company to work faster. Some of the key departments in a company may be the finance department or the sales department. 3) Chain of command is how management delegates authority to individuals throughout a workplace (Chain of Command). Instead of one manager delegating tasks, department managers can give instructions as they see fit. A normal chain of command would have the president at the top, followed by the vice-president, and so on. 4) Span of control is the number of employees that a manager has under his or her control at one time. Department managers would have a span of control over the employees who they are responsible for. 5) Centralization is the process where key decisions are taken only by top management. On the other hand, decentralization places trust in employees lower down the food chain and allows them to make decisions for

Wednesday, October 16, 2019

The Traditional Pedagogical Method of Learning Assignment

The Traditional Pedagogical Method of Learning - Assignment Example Teachers have to provide motivation and further encourage the student to continue exploring and questioning the matter. It is important for the students to learn to apply what the teacher has delivered as information. This educational goal can be achieved if they learn how to think abstractly. The teacher has to equip them with the tools to critically evaluate situations and problems and then determine by themselves the solution. This happens when the teacher uses strategies and concepts that build skills required for productive collaboration. Students have to construct their own meaning despite the directions and teaching methods of the teachers (Science for all Americans 1990). Through the principles of learning and teaching, the learning environment also encourages students to develop their independent and interdependent learning abilities. The teachers should establish an atmosphere where the students can learn both individually and with each other. Such tasks can be beneficial especially for young students who still orient themselves in the educational setting. Learning usually occurs when students have the opportunity not only to express their ideas but also to get feedback both from their peers and teachers (Science for all Americans 1990).

Assignment Essay Example | Topics and Well Written Essays - 250 words - 14

Assignment - Essay Example This allows each department to focus on one task, allowing the company to work faster. Some of the key departments in a company may be the finance department or the sales department. 3) Chain of command is how management delegates authority to individuals throughout a workplace (Chain of Command). Instead of one manager delegating tasks, department managers can give instructions as they see fit. A normal chain of command would have the president at the top, followed by the vice-president, and so on. 4) Span of control is the number of employees that a manager has under his or her control at one time. Department managers would have a span of control over the employees who they are responsible for. 5) Centralization is the process where key decisions are taken only by top management. On the other hand, decentralization places trust in employees lower down the food chain and allows them to make decisions for

Tuesday, October 15, 2019

Violence and Crime Essay Example for Free

Violence and Crime Essay In the last sentence, the immense power of the darkness is revealed when MacCaig points out that no stockades can keep the midnight out. The darkness seems so immensely powerful and lethal because stockades are barriers make to stop anything that comes against it. So if we cant keep the darkness away from NY, nothing can. I think that the message MacCaig is trying to get across to us is that Crime and violence can affect lots of people, even a whole city, and that its impossible stop it or fight it. He cleverly personified the darkness to get this message across to us. Edwin Morgans poem Glasgow 5th March 1971 is also about crime and violence in the society but Edwin Morgan has some different views of it but they also share some same views about it which you can see from the poems. Glasgow 5th March 1971 also sounds like a realistic title, just like MacCaigs title. Is sounds as if there was and incident there in real life. First of all, poet describes the broken glass as a ragged diamond. This creates a contrasted image as broken glass looks completely different to what it looked like when it was in one piece. The word ragged is good word choice because the word itself sounds bumpy and jagged and also like what it means. So its much easier to imagine the shape of the broken glass. Morgan comments on the Mans face as bristling with fragments of glass. The poet doesnt acknowledge us of any bloodiness or pain that the man is in, unlike MacCaig because when MacCaig writes about the injured people, he mentions broken bones and Harsh screaming which clearly indicates the pain the suffering people must be in. There is specific violence when Morgan notifies us that the girl spurts arterial when Morgan notifies us that the girl who is with the man, spurts arterial blood when she is pushed through a shop window. On the other hand, MacCaig only hints at violence and talks about the pain the victims are in like when he is talking about broken bones and screaming. By using the word arterial, he lets us know how deep the cut really is and it also makes the wound seem lethal. Morgan also uses alliteration in his poem in the same way as MacCaig uses it. They both use it when they are talking about the after affects of the crime and violence on people. There is alliteration when the letter w is repeated in wet look white coat. This reflects the soft sound of the blood is splattering on her coat as the w sound is also has that soft sound. The image created is very violent because red blood clearly stands out on a white coat. The red blood will clearly contrast with the white coat, clearly standing out. MacCaig also uses one violent image like this when he talks about the blood glazed sidewalks, which will also stand out. The two victims of the crime, man and girl, both have their arms starfished out and braced for impact. This clearly reveals to us that both people were taken by surprise from looking at the word starfished. Their shear fear is shown by the phrase braced for impact as they dont know what is happening to them presently and what could happen to them next. This is an example of extreme emotion. MacCaig uses extreme emotion as well but he used it to describe the pain the victims were in. Morgan describes either one or two people at a time whereas MacCaig describes what is happing to lots of people as they are affected by violence. Morgan has another phrase with alliteration when the faces of the victims show surprise, shock, as the s and sh sounds are repeated. This mirrors the sound of the broken glass as the two victims move about. At the end, Morgan reveals that the two youths, where the criminals who pushed the couple through the window. He also reveals two more witnesses in the background driving there car, but they purposely drive away and choose not to get involved. I think that the message Morgan is trying to get across is that crime and violence can happen to anyone, anywhere and that it is not being helped by people to stop it as more and more people are becoming apathetic and not getting involved. So they both share similar views. In conclusion, I think the both want their readers to know that crime and violence cant be stopped and that it can happen to anyone, wherever you go. They both write in different ways to get similar points across; Edwin Morgan writes specific violence whereas Norman MacCaig writes violence in general or non specific violence. After looking at both poems, I have learnt that crime and violence is everywhere and that everyone should put in effort, together, if we want it to be completely stopped. Edwin Morgans and Norman MacCaigs poems are based on two completely different cities. They are almost at the opposite side of the world to each other, yet, they still share similar ideas about crime and violence.

Monday, October 14, 2019

Role Of Science In Our Life Philosophy Essay

Role Of Science In Our Life Philosophy Essay He was nothing, quite an ordinary thing, of no importance at all. But he had a powerful but hidden tool. With the passage of time, he gradually discovered this tool, used it and turned into the most powerful creature of this planet. Who was he? Yes! This is the story of human being. And that tool used by him is science. The word science was derived from Latin word scientia (means knowledge). Science means to observe natural phenomenon occurring around us for collecting useful information and use these information for the benefit of mankind. It is regardless of the method adopted by someone. Human being of this era making researches in scientific fields with modern methods and machines and the man centuries before, observing nature and recording results, are same. Brief history of science: It is said that many centuries ago, man started his struggle in scientific field by the act of burning at such a time when he was even not familiar to the word science. As Aristotle said, man is a thinking animal. Thus man started thinking about things around him. He derived useful results from observations and started using them to make his life facilitated. It was beginning of science. Time kept on passing. As the result of struggle made by thousands of people in science, life on Earth reached the current state. No doubt science directed this journey at every step. Human beings of all times participated in development of science. Remarkable progress was made by Greeks. They discovered many things. Muslims scientists also worked in this field for five to six hundred years. They made great discoveries. For example Jabir Bin Hayan was a great scientist of chemistry. He discovered sulphuric acid as well as nitric acid. Ibn- al-Hythem made progress in optics. While Alberooni was a great geologist. How science affected daily life? Now-a-days although it is not impossible but much difficult to imagine life without different scientific inventions. For example we need vehicles to travel, cell phone and internet to communicate and other such things. We cant live without them. Science made advancements in many fields for example. A few of them are described as follow. Positive effects: Increased average human life: In the beginning life was in danger all the time. It might be harmed by many factors. If one had been born two hundred years ago, he would have had one chance in eight of living to be one year old. He would have suffered from many diseases like small pox, measles, whooping cough, scarlet fever and diphtheria before he was twelve. Yellow fever, malaria, typhus, cholera once started, spread through a community and thousands of people were to lose their lives. Life was most uncertain. A person who used to live more than thirty to forty years was indeed lucky. It is unbelievable that such conditions existed so short a time ago. The advancements made by research in medical science minimized all such risks. Today babies are born in hospitals where there is a little chance of their getting disease. They are enabled to fight against many diseases by vaccination at early stage. Different types of supplements are used in their better growth. Purification of water and food is also an important thing introduced by science in this aspect. Besides this all, medical science discovered remedy for each disease man may suffer from. A person can expect to live to be almost seventy years old. In other words, more than thirty years have been added to normal human lifes length. Improved life standard: In the beginning man is assumed to have no sense of wearing clothes, building houses, growing crops and other such things. He used to live in caves, get eatables from surroundings. When he started thinking about everything around him (making progress in scientific field in other words), he observed different things and use them for his benefit. For example he started building houses, got sense of wearing clothes, started producing different eatables and so many other things. Later on he set rules for everyone living in one community for his welfare. Thus gradually he kept on improving his life style. Transport system: Hundreds of years ago, necessities of human beings were limited. Distance between man and his needs was not large. they were able to get everything he wanted from his surroundings. Men used animals kike horse while hunting and camels and some other animals while travelling from one place to another. It took sufficiently long time if they had to go to distant places. Person related to one another mostly used to live on a single piece of land in the form of tribes. Therefore they didnt have to go anywhere to meet their relatives. But later on, as population increased, the small pieces of land were unable to provide them with their basic needs. Therefore they had to go anywhere else in search of food and other things. At that time man needed something which could make travelling easier. In this way he struggled in this field and discovered wheel. It was a huge discovery. No one knows that who discovered it for first time but it is the fact it brought a great revolution. Later on with the invention of engine and other machines, travelling became easier. Now-a-days there are fastest automobiles and supersonic planes to serve us. And at the same time for transportation of goods, we have ships. Therefore it has become very easy to travel to far off places with as much stuff as we want. It provided a lot of facilities to importers and exporters as well. With the help of modern travelling means, a person is able to return home in the evening after doing his job for the whole day at a place hundreds of miles away from his home. Thus science lessened the distances and made life faster and faster. Communication: As described above, in the past, people related to each other used to live together in the form of tribes. They could easily convey their message to the person they wanted. With the passage of time, distances between individuals were increased. Therefore people used to look for some other means of communication. At early stages, they used light blinkers for giving message to someone in the form of code at night. For conveying message to a far off place, they used to send letters through men or birds. With the invention of loud speaker, it became very easy to address to a gigantic crowed. A remarkable advancement in this field was made by Graham Bell. He was the man who invented telephone for the first time. That device namely telephone was improved later on. It served mankind in a great way. Modern cell phones are most modified form of that device. Another device namely Radio also proved very useful in communicating many people at the same time. It was for one way communication only. Its major advantage was no use of wire in communication. Thomas was the person who invented a device called T.V. It was an awesome achievement in the history of information technology. Now people were able to enjoy both sound and picture. News paper is another source of news transmission. With the help of all these sources, current updates and a lot of entertainment is available all the time for everyone. Another huge thing in the history of telecommunication is inter-net. Internet is like an ocean o f information, people and much more. One can find answer of any question by using it. He may contact to anyone, anywhere in the world. Any type of information can be shared at any level. All of these things were achieved with the help of science. Power development: It was science who taught us how to use energy available in different forms around us. Man used to burn woods to get heat (energy). All the energy from sun was wasted. By using scientific methods, we developed different techniques to make use of energy. For example, discovery of the electric current was a great job in this aspect. Later on we discovered how to convert different type of energy into electrical energy. Now we are able to use mechanical energy, solar energy and bio mass for current production. Nuclear power plants are based upon a comparatively new technology. With the help of this we make use of huge amount of energy evolved during fission and fusion. Electric current made life much facilitated and luxurious. Besides these, running vehicles by burning fuel is also an example of using chemical energy for useful purposes. Negative effects: This is a natural thing that everything which has some advantages must necessarily have some disadvantages as well. In exactly the same way, science has some negative effects too. As said by Isaac Asimov, the saddest aspect of life right now is the science gathers knowledge faster than society gathers wisdom. Although most of them are not much prominent or easily understandable but this is the fact that science is leading this planet towards a state which is quite unpredictable. That may be horrible enough not to support life. Let us see what negative effects of science are. Youngsters, being affected by media: We used science and made a lot of progress in I.T. Now-a-days almost everyone is familiar to the television, computer, cell phone and other such appliances. Especially our young generation uses to spend most of the time in texting, chatting on internet and watching programs on T.V. These are the requirements to be fulfilled if one wants to call himself Modern. They are not aware of importance of limited time. They use to spend their time in such useless things and take it to be a source of honor. It is a kind of addiction. They cant give this up. They, living in an imaginary world, feel many difficulties in real life because real life is much different than that shown on screen. They are unable to concentrate upon their studies. Most of them are aimless. They try to follow the characters shown to them in movies, plays and video games. Sometimes its not a fair practice. They use to adopt many bad habits. This is an alarming situation. Another related effect of media is stopping youngs ters from outdoor activities. They spend most of the time in front of PCs and are losing their interest in outdoor games. This results the physical weakness as well as the feeling of loneliness. They are losing their confidence. Some of them feel shy while facing people. Thus excessive use of these useful inventions is creating a new generation with strange qualities. Development of destructive weapons: Another great misuse of science is weaponsdevelopment. Man started making weapons for hunting and defense purposes. As science raised everything, weapons also kept on being more and more harmful with the passage of time. Unaware of the results, man even made nuclear bomb for his own destruction. Mahatma Gandhi said, Science without humanity is a sin. But nuclear bomb has been handed over to wild politicians who are using it as a tool to show off their power. Bombs may blow the planet up in minutes, a few blastsà ¢Ã¢â€š ¬Ã‚ ¦. and deep silence forever! Just imagine! Science made future of planet earth so uncertain. Pollution: Many scientific activities and appliances are participating in causing pollution. For example burning of fuel in vehicles and factories causes many harmful factors polluting environment. Most common of them are carbon dioxide and carbon monoxide. Both of these are suffocating. Carbon dioxide is playing main role in global warming. Another pollutant ClCF2 was found responsible for ozone layer destruction. It is produced by air conditioners and refrigerators commonly used on earth. The polluted water from industries gets mixed with water used for drinking and causes lots of diseases. Waste materials from factories also change acidity of soil as well. Vehicles, making noise, also participate in noise pollution. Drugs: Use of science in drug development is another frightening thing. Science made drugs cheaper and thus easily available. New drugs are being introduced by using various scientific methods. Almost everyone use to smoke and snuff. Other drugs like opium and heroin are also being used frequently. All this shows that science is indeed a great power. It has magical effects. Everyone can make progress in this field. Everything around us is a mystery. We just have to reveal these secrets. As Marie Curie said, Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fearless. There is an order in occurrence of each phenomenon in the universe. As Elbert Einstein said God does not play dice with universe. We just have to understand that order. This is science. The direction of this journey must always be set by religion. Because religion allows us to take steps for human welfare only.

Sunday, October 13, 2019

Fodors Functionalism Essays -- Body Mind Psychology Essays Searle

Fodor's Functionalism Fodor begins his article on the mind-body problem with a review of the current theories of dualism and materialism. According to dualism, the mind and body are two separate entities with the body being physical and the mind being nonphysical. If this is the case, though, then there can be no interaction between the two. The mind could not influence anything physical without violating the laws of physics. The materialist theory, on the other hand, states that the mind is not distinct from the physical. In fact, supporters of the materialist theory believe that behavior does not have mental causes. When the materialist theory is split into logical behaviorism and the central-state identity theory, the foundation of functionalism begins to form. Logical behaviorism states that every mental feeling has the same meaning as an if-then statement. For example, instead of saying "Dr. Lux is hungry," one would say "If there was a quart of macadamia brittle nut in the freezer, Dr. Lux would eat it." The central-state identity theory states that a certain mental state equals a certain neurophysiological state. The theory works in a way similar to Berkeley’s representation of objects. Both mental states and objects are a certain collection of perceptions that together identify the particular state or object.   Ã‚  Ã‚  Ã‚  Ã‚  Fodor develops the idea of functionalism by combining certain parts of logical behaviorism and the central-state identity theory. From logical behaviorism, Fodor incorporates the idea that mental processes can be represented by physical if-then statements. As such, behavior and mental causation are no longer distinct and unable to interact. Also, logical behaviorism provides a way for mental causes to interact with other mental causes. This, in turn, may result in a behavioral effect. The last point is also a characteristic of the central-state identity theory. One doctrine of the central-state identity theory is called "token physicalism." Token physicalism states that all mental states that currently exist are neurophysiological. Thus, token physicalism does not place physical restrictions on the type of substance capable of having mental properties. When the points of logical behaviorism and the central-state identity theory, as described here, are combined, fu nctionalism is the result. The theory of functionalism supposes that a m... ...whether the simulation of mental processes resulting from a computer program are real mental processes?   Ã‚  Ã‚  Ã‚  Ã‚  At the end of chapter two, Searle summarizes his criticism of functionalism in the following way. The mental processes of a mind are caused entirely by processes occurring inside the brain. There is no external cause that determines what a mental process will be. Also, there is a distinction between the identification of symbols and the understanding of what the symbols mean. Computer programs are defined by symbol identification rather than understanding. On the other hand, minds define mental processes by the understanding of what a symbol means. The conclusion leading from this is that computer programs by themselves are not minds and do not have minds. In addition, a mind cannot be the result of running a computer program. Therefore, minds and computer programs are not entities with the same mental state. They are quite different and although they both are capable of input and output interactions, only the mind is capable of truly thinking and understanding. T his quality is what distinguishes the mental state of a mind from the systemic state of a digital computer.

Saturday, October 12, 2019

Resolving Conflict between Science and Religion: Reform Judaism and Sci

Resolving Conflict between Science and Religion: Reform Judaism and Scientific Thought    The relationship between science and religion is not easy to navigate. On the most basic level, they are viewed as different types of thought. Religion, it seems, deals with the subjective, spiritual realm. Science, on the other hand, seems to deal with facts. It may then appear easy to separate the two realms of thought, and philosophers, theologians and scientists have from time to time attempted to do this. Both science and religion make hypotheses about the fundamental nature of human existence and the nature of the universe, however, and inevitably the claims of each come into conflict. Whether this conflict occurs on a personal level or between opposing institutions, the claims of one often seem to place the other in dire jeopardy. We have seen demonstrations of such conflict throughout history, especially in relation to the Christian faith. For instance, few people have not heard about the adverse reaction of the Catholic Church when Galileo propounded his theory of a heliocentric universe. Even today, we are not free of conflicts that arise when religious doctrine conflicts with scientific theorizing. A prominent issue is creation, in which scientific theories about the big bang directly contradict the religious doctrine of the Christian faith, which understands creation through the story of Genesis in the Old Testament. It is an oversimplification to pit science and religion as bitter opposites, but it is undeniable that in many faiths there exists a continuing conflict between advancing scientific theories and the religious perspective. How, then, can one expect to be able to integrate a scientific understanding of the wor... ... faith that binds them to one another and to God. Bibliography Armstrong, Karen. A History of God. New York: Alfred A Knopf, 1993. Barbour, Ian. Religion and Science: Historical and Contemporary Issues. San Francisco: HarperSanFrancisco, 1997. "Human Stem Cell Research (5761.7)." CCAR Responsa. 30 April 2003 . Meyer, Michael A. and W. Gunther Plaut. The Reform Judaism Reader: North American Documents. Cambridge: UAHC Press, 2000. Nuesner, Jacob. Judaism in Modern Times: An Introduction and Reader. Cambridge: Blackwell Publishers, 1995. "On the Treatment of the Terminally Ill (5754.14)." CCAR Responsa. 30 April 2003 . Plaut, W. Gunther. The Rise of Reform Judaism. New York: World Union for Progressive Judaism, Ltd., 1963.

Friday, October 11, 2019

A warm welcome to BN2102 Bioengineering data analysis Essay

Understand the statistical analysis that commonly accompanies publication of experimental data in scientific literature.   Perform the appropriate statistical analysis for a given set of experimental data. Estimate a parameter of interest by performing a suitable fitting to a set of experimental data. Create a suitable mathematical model based on the available experimental data. The module is divided in two parts. The first part will be taught by Chen Peiyi of the Department of Statistics and Applied Probability while the second part will be taught by Dr Alberto Corrias of the Department of Bioengineering. Some of the sessions will be conducted in the computer cluster rooms (block E2, level 3). For those sessions, the class is divided in 4 groups. Please check the IVLE to see which group you belong to and the Lesson Plan to check the exact locations and timings. The assessment is a combination of Continuous Assessment (CA) and final exam a s follows: CA of part 1: 20% CA of part 2: 20% Final exam: 60% The nature of the CA will be specified by each lecturer in due course. The final exam will be closed book. No aid†sheet will be allowed. Statistical tables will be provided if necessary. Please bring your calculator, however please note that programmable calculators will NOT be allowed. We hope you will enjoy BN2102! Best wishes, The teaching staff.

Thursday, October 10, 2019

Why Is Strategy Important to Business?

Strategy is determining where you are now, where you want to go, and how to get there. It’s the art of developing and implementing specific actions and decisions that will help a business to achieve goals and objectives as set out by the owners. Through the strategy process the overall direction of the company is set including opportunities and threats in the outside world and the internal strengths and weaknesses of the business. The aim of a business strategy is to ensure that the threats posed by the external environment are minimized and also to strengthen or minimize the effects of internal weaknesses. The opportunities and strengths are combined to ensure maximum productivity is achieved. The more the external environment changes the more opportunities there are likely for a company, but the more threats can be a problem if not prepared for. Without a business strategy, it would be difficult for an owner to realize the opportunities available. Strategic management in contrast with business policy is a technical approach having a five step model. Strategic management is a set of managerial decisions and actions that determine the long run performance of a company. Strategic management does not have to be just a part of the top level management. In fact, organizations should focus on strategic management at all levels of the management and the entire hierarchy of the company should be involved both in planning and implementation phases. Strategic management does not have to be just a part of the top level management. Organizations should focus on strategic management such that all levels of the management and the entire hierarchy of the company should be involved in both planning and implementation phases. The basic theory of strategic management involves the action of creating and implementing plans and decisions for the benefit of the organization and to help it achieve its objectives. Strategic management analyzes and scan the environment therefore future problems and opportunities could be well anticipated, allows a firm’s top management to anticipate changes and provide track and control for the enterprise, provides clear cut mission, also gives vision and objectives of enterprise to all the employees, and allows a firm to take decisions on the basis of long range forecast. Your vision must be future-oriented it has to paint a picture that attracts employees through the use of visual imagery. This is what gets people hooked into buy-ins, followership, and implementation of the plan. So it means you just have to think outside the box of today and describe the world of the future. With the current situation of the economy the fact that some business establishments have stopped their operation and closed has caused big drop in small and large corporations. Having back up plan would be the idea should the original plan does not succeed businessmen could have alternative options or backed up plans for the continuity and success of the business. Since businessmen are knowledgeable of the business processes, they know the importance of having back up plans. Without a contingency plan, and should the original plan fail, businessmen and the business could experience a lot of trouble. The Mission statement is important because it describes the reason for the existence of an organization and what it hopes to achieve. While mission statements vary from organization to organization and represent the distinctness of each one, they all share similar components. Before writing a mission statement, leaders in the organization must have an idea of what is in store for the future. This vision is the foundation for the mission statement. Most statements include descriptions of the organization's target market, the geographic domain, their concern for survival, growth and profitability, the company philosophy, and the organization's desired public image. In addition, it is a tool that conveys the goal, organizational structure and strategy, legitimacy, values, participation and ownership among employees, leadership, responsibility to the community, ethical priorities, and commitment to the public and stakeholders. The organizational decision making process involves proper and efficient implementation of strategic plans and methods to achieve desired business objective. Often one difficulty facing an organization is that multiple divisions are involved in the overall decision making process. Making a decision can have different implications for each respective division. With the businesses of today facing shortened product lifecycles, organizations are facing intense competitive pressures to build market share to stay ahead of rivals. Process changes, the introduction of new and improved disruptive technologies are forcing companies to adapt new business goals and objectives in shortened timeframes, this alone places stresses on all organization. References Karger (1991). Strategic Management: The Key to Corporate Success Pearce II, J.A., & Robinson, Jr., R.B. (2008). Strategic management. (11th ed.). New York, NY: McGraw-Hill. Mission and Vision Statements http://www.referenceforbusiness.com/management/Mar-No/Mission-and-Vision-Statements.html#ixzz1LGZLzvbI